Curriculum Vitae

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Wael Y. Musleh, M.D., Ph.D.

BOARD CERTIFICATION

AMERICAN BOARD OF NEUROLOGICAL SURGERY

EDUCATION

Complex Spine Oncology Fellowship, (Mentor: Ehud Mendel,MD.) 7/2007-6/2008
OHIO STATE UNIVERSITY

Neurosurgery Residency, (Chairman: Richard Fessler, MD. Ph.D.) June 2007
UNIVERSITY OF CHICAGO HOSPITALS

Doctor of Medicine, May 2001
SAINT LOUIS UNIVERSITY

Doctor of Philosophy, Neurobiology, December 1996
UNIVERSITY OF SOUTHERN CALIFORNIA

Master of Science, Biomedical Engineering, May 1992
UNIVERSITY OF SOUTHERN CALIFORNIA

Bachelor of Science, Biomedical Engineering, May 1990
UNIVERSITY OF SOUTHERN CALIFORNIA

EXPERIENCE

Neurosurgeon, Rebound Neurosurgery, Southwest Medical Center, July 2008-present.

Complex Spine/Spine Oncology Fellowship, Ohio State University, July 2007-June 2008.

Neurosurgery Residency, University of Chicago, June 2001-June 2007.

Post Doctoral Research, USC, Gerontology, January 1997-August 1997

Electrophysiology Consultant, USC, Neurobiology, May 1992-August 1993

Research Assistant, USC, Biomedical Engineering Department and Neurobiology, January 1990-September 1991

AWARDS & ACCOMPLISHMENTS

  • Honors and Near honors at Saint Louis University School of Medicine (1997-2000)
  • Co-founder of Surgery Interest Group at Saint Louis University (1998)
  • Gerontology Training Grant Fellowship (1994-1996)
  • Research Assistantship (1993-1996)
  • Director of the “Synaptic Plasticity: LTP and LTD” homepage for the USC Human Brain Project (1995)
  • Dean’s List Awards (1987-1990)

GRANTS

Neurosurgery Research and Education Foundation (2006) – Grant award: 40,000 USD. The objective of the project is to investigate the role of calpain in vasospasm and its effects on the biochemical and electrophysiological properties of potassium channels.

PRESENTATIONS

Seminars

  • Low Incidence of Subdural Grid Related Complications in Prolonged Pediatric EEG Monitoring (2003)
  • Localization and expression of LTP Expression (1996)
  • Glycine-induced long-term potentiation is associated with modifications of AMPA receptors (1996)
  • Effects of NMDA and AMPA receptor antagonists on paired-pulse facilitation (1995)
  • Effects of nitric oxide synthase inhibitors and a NO scavenger on LTP induction and maintenance (1994)
  • Effects of EUK-8, a SOD mimic, on hypoxia- and acidosis-induced damage in hippocampal slices (1993)

Posters

  • A novel minimally invasive Technique for spinal cord untethering. AANS (2005)
  • Novel medial to lateral differences in the expression of short- and long-term synaptic plasticity in the striatum. Annual Neuroscience Meeting, New Orleans (1997)
  • Effects of ethanol on NMDA receptor-mediated responses in three mouse genotypes. Maui (1995)

COMMUNITY SERVICE

  • Member of The Crossover Trust (1999)
  • Volunteer, Health resource Center (1999)
  • AIDS Education Task Force (1998)
  • Volunteer, University of Southern California County Hospital (1989)

HOBBIES AND RECREATIONAL ACTIVITIES

  • Guitar
  • Soccer
  • Racket ball
  • Chess
  • Symphony/Theater

PUBLICATIONS

Musleh,W., Baig, M., Porensky, P., Zarzour, H., and Mendel, E. (In preparation) Spontaneous development of a de novo lumbar arachnoid cyst following a thoracic tumor resection.

Tredway, T.L., Musleh, W., Christie, S.D., Khavkin, Y., Fessler, R.G. and Curry, D.J. (2007) A Novel Minimally Invasive Technique for Spinal Cord Untethering. Oper. Neurosurg. 60 (2): 70-74.

Musleh, W., Sonabend, A.M., and Lesniak, M.S. (2006) Role of craniotomy in the management of pituitary adenomas and sellar/parasellar tumors. Expert Rev Anticancer Ther. Sep;6 Suppl 9:S79-83.

Musleh, W., Yassari, R., Hecox, K., Kohrman, M., Chico, M., and Frim, D. (2006) Low incidence of subdural grid related complications in prolonged pediatric EEG monitoring. Pediatr. Neurosurg.. 42 (5): 248-287.

Song, J.K., Musleh, W., Christie, S.D., and Fessler, R.G. (2006) Cervical juxtafacet cysts: case report and literature review. Spine J. 6 (3):279-81.

Sonabend, A.M., Musleh, W., and Lesniak, M.S. (2006) Oncogenesis and mutagenesis of pituitary tumors. Expert Rev Anticancer Ther. Sep;6 Suppl 9:S3-14.

Musleh, W., Bi, X., Yaghoubi, S., Tocco, G. and Baudry, M. (1997) Glycine-induced long-term potentiation is associated with structural and functional modifications of -amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid receptors. PNAS, 94 (17): 9451-9456.

Musleh, W., Yaghoubi, S. and Baudry, M. (1997) Effects of a nitric oxide synthase inhibitor on NMDA receptor function in organotypic hippocampal cultures. Brain Res. 770 (1-2): 298-301.

Musleh, W., Alvarez, S., Baudry, M. and . Alkana, R. (1996) The effect of ethanol on NMDA receptor-mediated responses in three mouse genotypes. Alcoholism: Clin. and Exp. Res., 20 (7): 1299-1304.

Musleh, W., Bruce, A., Malfroy, B. and Baudry M. (1994) Effects of EUK-8, a synthetic, catalytic superoxide scavenger, on hypoxia- and acidosis-induced damage in hippocampal slices. Neuropharm. 33 (7): 929-934.

Musleh, W., Shahi, K. and Baudry, M. (1993) Further studies concerning the role of NO in LTP induction and maintenance. Synapse, 13 (4): 370-375.

Garcia, R., Musleh, W., Tocco, G., Thompson, R.F. and Baudry, M. (1997) Time-dependent blockade of LTP and STP in hippocampal slices following acute stress in mice. Neurosci. Lett. 233 (1): 41-44.

Doctrow, S., Huffman, K., Marcus, C. B., Musleh, W., Bruce, A., Baudry, M. and Malfroy, B. (1997) Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy. Adv. Pharmacology, 38: 247-269.

Tocco, G., Musleh, W., Sakhi, S., Schreiber, S. S., Baudry, M. and Pasinetti, G. M. (1997) Complement and glutamate neurotoxicity. Genotypic influences of C5 in a mouse model of hippocampal neurodegeneration. Mol. Chem. Neuropath. 31 (3): 289-300.

Pasinetti, G. M., Tocco G., Sakhi S., Musleh W. D., Desimoni M. G., Mascarucci P., Schreiber S., Baudry M. and Finch C. E. (1996) Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions. Neurobio. Dis., 3 (3): 197-204.

Smith, R. Musleh, W. Akopian, G. Buckwalter, G. and Walsh, J.P. (2001) Regional differences in the expression of corticostriatal synaptic plasticity. Neuroscience. 106(1):95-101.

Akopian, G., Musleh, W., Smith, R., and Walsh, J.P. (2000) Functional state of corticostriatal synapses determines their expression of short- and long-term plasticity. Synapse. Dec 1;38(3):271-80.

Musleh, W., Ferguson, S., Gurbuxani, S., Shafizadeh, S.F., and Lesniak, M.S. (submitted) Intracranial MALT lymphoma: case report and review of the literature. Surg. Neurol.

ABSTRACTS

Tredway, T. L., Musleh, W., Curry, D., and Fessler, R. (2005). A Novel Minimally Invasive Technique in Spinal Cord Untethering.

Musleh, W., Hecox, K., Kohrman, M., Chico, M., and Frim, D. (2003) Low Incidence of Subdural Grid Related Complications in Prolonged Pediatric EEG Monitoring.

Musleh, W., Akopian, G. and Walsh, J. P. (1997) Novel medial to lateral differences in the expression of short- and long-term synaptic plasticity in the striatum. Abs. Soc. neurosci. Meet.

Tocco, G., Musleh, W. and Pasinetti, G. Inflammatory mechanisms of neurodegeneration. (1995) The role of the complement derived anaphylatoxin C5a. Abs. Soc. Neurosci. Meet. 21: 1722.

Bruce, A., Musleh, W., Malfroy, B., and Baudry, M. (1993) Effects of a salen-manganese complex, a SOD-mimic, in various models of neuronal pathology. Abs. Soc. Neurosci. Meet.